{"id":292,"date":"2020-05-02T13:07:35","date_gmt":"2020-05-02T10:07:35","guid":{"rendered":"https:\/\/www.imucore24.com\/?page_id=292"},"modified":"2020-05-10T12:57:15","modified_gmt":"2020-05-10T09:57:15","slug":"b7-vitamini-ozellikleri","status":"publish","type":"post","link":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/b7-vitamini-ozellikleri\/","title":{"rendered":"B7 Vitamini ve \u00d6zellikleri"},"content":{"rendered":"\t\t
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B7 Vitamininin Yararlar\u0131, Eksikli\u011fi, Fazlal\u0131\u011f\u0131 ve Daha Fazlas\u0131<\/h1>

H vitamini yada Biotin olarak da bilinen B7 vitamini, v\u00fccudun g\u0131dalar\u0131 enerjiye d\u00f6n\u00fc\u015ft\u00fcrmesine yard\u0131mc\u0131 olan B kompleks vitaminlerinden biridir .<\/h4>

\u201cBiotin\u201d kelimesi, \u201cya\u015fam\u201d veya \u201cdevam\u201d anlam\u0131na gelen eski Yunanca \u201cbiotos\u201d kelimesinden gelir. B vitaminleri ve \u00f6zellikle biotin, cildinizin, sa\u00e7\u0131n\u0131z\u0131n, g\u00f6zlerinizin, karaci\u011ferinizin ve sinir sisteminizin sa\u011fl\u0131kl\u0131 kalmas\u0131na yard\u0131mc\u0131 olur. Ayr\u0131ca hamilelik s\u0131ras\u0131nda, embriyonik b\u00fcy\u00fcme i\u00e7in \u00f6nemli ve g\u00fcvenilir bir besin kayna\u011f\u0131d\u0131r.<\/h4>

\u00c7o\u011fu insan, ihtiya\u00e7 duydu\u011fu biotini sa\u011fl\u0131kl\u0131 bir beslenme tarz\u0131 ile g\u0131dalardan alabiliyor, ancak daha fazla biotin alman\u0131n kan \u015fekerinizi d\u00fczenleyebilece\u011fi, sa\u011fl\u0131kl\u0131 sa\u00e7, cilt ve t\u0131rnak olu\u015fumunu g\u00fc\u00e7lendirece\u011fi, hamile kad\u0131nlar\u0131n daha sa\u011fl\u0131kl\u0131 bebekler do\u011furmas\u0131na yard\u0131mc\u0131 olabilece\u011fi y\u00f6n\u00fcnde bir\u00e7ok \u00e7al\u0131\u015fma bulunmaktad\u0131r.<\/h4>

B7 vitamini nedir?<\/h2>

Biotin olarak bilinen B7 Vitamini sekiz vitaminden olu\u015fan B-kompleks vitamin grubu<\/strong><\/a>nun bir \u00fcyesidir. T\u00fcm B vitaminleri gibi, biotin de v\u00fccudunuza karbonhidratlar\u0131, ya\u011flar\u0131 ve enerji \u00fcretimi i\u00e7in proteinleri par\u00e7alamada yard\u0131mc\u0131 olur. Ayn\u0131 zamanda sa\u011fl\u0131kl\u0131 cilt, sa\u00e7 ve sinir sistemi i\u015flevinin korunmas\u0131nda rol oynar ve hamile kad\u0131nlara ve baz\u0131 diyabet hastalar\u0131na yard\u0131mc\u0131 olabilir.<\/p>

\u00c7ok az yan etkiye sahip suda \u00e7\u00f6z\u00fcn\u00fcr bir vitamin oldu\u011fundan idrarla at\u0131ld\u0131\u011f\u0131 i\u00e7in neredeyse hi\u00e7 toksisite yoktur. Ancak, yan etkileri nadiren g\u00f6r\u00fclse bile, takviye olarak t\u00fcketmeden \u00f6nce doktorunuza dan\u0131\u015fman\u0131z \u00f6nemlidir.<\/p>

B7 Vitamini \u2019nin \u0130\u015flevleri ve Yararlar\u0131<\/h2>

1. B7 Vitamini Sa\u00e7 D\u00f6k\u00fclmesini Durdurabilir.<\/h3>

B7 vitamini eksikli\u011fi, biri sa\u00e7 d\u00f6k\u00fclmesi olan bir\u00e7ok olas\u0131 belirtiye sahiptir . Biotin’in sa\u00e7 d\u00f6k\u00fclmesini durdurabilme yetene\u011fi bir\u00e7ok klinik \u00e7al\u0131\u015fmada de\u011ferlendirilmi\u015ftir. Biotin eksikli\u011fi, \u00e7e\u015fitli altta yatan nedenlerle ili\u015fkilendirilebilse de, biyotin takviyesinin biyotin eksikli\u011fine ba\u011fl\u0131 sa\u00e7 d\u00f6k\u00fclmesinin restorasyonunda etkili oldu\u011fu g\u00f6r\u00fclmektedir (1)<\/sub><\/strong>.<\/p>

Valproik asit, antiepileptik ila\u00e7, baz\u0131 denemelerde serum biyotinidaz aktivitesini azaltarak biyotin eksikli\u011fine neden olmakla ili\u015fkilendirilmi\u015ftir (2)<\/sub><\/strong>.<\/p>

Bir \u00e7al\u0131\u015fmada, valproik asit ile tedavi, cilt sorunlar\u0131 ve sa\u00e7 d\u00f6k\u00fclmesi gibi doza ba\u011fl\u0131 advers olaylarla ba\u011flant\u0131l\u0131yd\u0131. Hastalara ve kontrol grubuna biyotinidaz eksikli\u011finin bu semptomlara yol a\u00e7\u0131p a\u00e7mad\u0131\u011f\u0131n\u0131 belirlemek i\u00e7in klinik ve laboratuvar de\u011ferlendirmeleri yap\u0131ld\u0131. Valproik asidin dolayl\u0131 olarak azalm\u0131\u015f biyotinidaz enzim aktivitesine ve \/ veya biyotin eksikli\u011fine neden oldu\u011fu bulundu (2)<\/sub><\/strong>.<\/p>

Ba\u015fka bir \u00e7al\u0131\u015fma ise yukar\u0131daki bulgularla \u00e7eli\u015fmektedir. \u00c7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131 valproik asit tedavisinin biyotinidaz aktivitesini etkilemedi\u011fini g\u00f6stermi\u015ftir. Valproik asitle tedavi edilen 57 \u00e7ocuktan 3’\u00fc sa\u00e7 d\u00f6k\u00fclmesi ya\u015fad\u0131, bu da 3 ay sonra g\u00fcnde 10 mg biotin ile takviye edildikten sonra \u00e7\u00f6z\u00fcld\u00fc. Serum biotin ve biyotinidaz aktivitesi bu hastalarda deneme s\u00fcresi boyunca normal kald\u0131 (3)<\/sub><\/strong>.<\/p>

2. B7 Vitamini, kardiyovask\u00fcler sa\u011fl\u0131\u011f\u0131 iyile\u015ftirebilir.<\/h3>

B7 vitamini, serum trigliserit seviyelerini azaltmaya yard\u0131mc\u0131 olur. Bir hayvan \u00e7al\u0131\u015fmas\u0131nda, biotin takviyesi serum trigliseritlerini % 35 azaltm\u0131\u015ft\u0131r (4)<\/sub><\/strong>.<\/p>

Kandaki y\u00fcksek trigliserit seviyeleri, kalp hastal\u0131\u011f\u0131 riskini artt\u0131rd\u0131\u011f\u0131 i\u00e7in bu \u00f6nemli bir bulgudur (5)<\/sub><\/strong>.<\/p>

1980 y\u0131l\u0131nda biotin deste\u011finin plazma lipid seviyeleri \u00fczerindeki etkilerini incelemek i\u00e7in \u00e7ift k\u00f6r bir klinik \u00e7al\u0131\u015fma yap\u0131ld\u0131. \u00c7al\u0131\u015fmada rastgele 2 gruba ayr\u0131lan 40 ila 30 ya\u015f aras\u0131 kad\u0131n ve erkek vard\u0131. Bir grup g\u00fcnl\u00fck 0.9 mg biotin al\u0131rken, di\u011fer grup 71 g\u00fcn boyunca plasebo ald\u0131.<\/p>

Biotin ile tedavi edilen grupta, total lipid, toplam fosfolipid ve di\u011fer plazma bile\u015fenlerinde plasebo grubuyla kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda istatistiksel olarak anlaml\u0131 pozitif de\u011fi\u015fiklikler g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. Biotin seviyeleri ile total plazma lipidleri aras\u0131nda ters bir ili\u015fki vard\u0131 (6)<\/sub><\/strong>.<\/p>

3. B7 Vitamini t\u0131rnaklar\u0131n\u0131z\u0131 g\u00fc\u00e7lendirir.<\/h3>

1990 y\u0131l\u0131nda Amerikan Dermatoloji Akademisi Dergisi’nde yay\u0131nlanan klinik bir \u00e7al\u0131\u015fmada B7 vitamini kullanan \u00e7ivili t\u0131rnaklar\u0131 olan bir grup kad\u0131nda, alt\u0131 ay boyunca t\u0131rnak kal\u0131nl\u0131\u011f\u0131n\u0131n % 25 oran\u0131nda artt\u0131\u011f\u0131 g\u00f6sterilmi\u015ftir (7)<\/sub><\/strong>.<\/p>

O zamandan bu yana yap\u0131lan birka\u00e7 ba\u015fka \u00e7al\u0131\u015fma da benzer sonu\u00e7lar g\u00f6stermi\u015ftir. Makalelerin 2017 y\u0131l\u0131 incelemesi, biotin’in \u00e7e\u015fitli t\u0131rnak ko\u015fullar\u0131n\u0131n tedavisinde \u00fcmit verici sonu\u00e7larla birlikte kullan\u0131ld\u0131\u011f\u0131 sonucuna varm\u0131\u015ft\u0131r. \u0130yi kontroll\u00fc klinik \u00e7al\u0131\u015fmalar\u0131n yetersizli\u011fi nedeniyle, optimum dozu belirlemek ve etkinli\u011fini do\u011frulamak i\u00e7in daha b\u00fcy\u00fck \u00f6l\u00e7ekli \u00e7al\u0131\u015fmalara ihtiya\u00e7 vard\u0131r (8)<\/sub><\/strong>.<\/p>

4. B7 Vitamini, tip 2 diyabet konusunda yard\u0131mc\u0131 olabilir.<\/h3>

Glukokinaz (GK), glukoz metabolizmas\u0131nda \u00f6nemli rol oynayan bir enzimdir. Biotin, ins\u00fclin sekresyonunu kontrol eden glukokinaz aktivitesini uyar\u0131r (9)<\/sub><\/strong>.<\/p>

Beslenme Biyokimyas\u0131 Dergisi’nde yay\u0131nlanan 2013 y\u0131l\u0131nda yap\u0131lan bir \u00e7al\u0131\u015fmada, biotin ile 8 haftal\u0131k takviye, a\u00e7l\u0131k glukoz seviyeleri veya ins\u00fclin tolerans\u0131 \u00fczerinde hi\u00e7bir etkisi olmadan ins\u00fclin sekresyonunu artt\u0131rd\u0131 ve glukoz tolerans\u0131 iyile\u015ftirildi. Bu bulgular, biotinin beta h\u00fccre fonksiyonu ve bununla birlikte diyabet tedavisi ve \u00f6nlenmesi \u00fczerinde olumlu bir etkiye sahip olabilece\u011fini g\u00f6stermektedir (10)<\/sub><\/strong>.<\/p>

Diyabetin bir\u00e7ok komplikasyonundan biri periferik n\u00f6ropatidir, duyu kayb\u0131na, uyu\u015fuklu\u011fa ve bazen ayaklarda, bacaklarda ve ellerde a\u011fr\u0131ya neden olan bir sinir hasar\u0131 \u015feklidir (11)<\/sub><\/strong>.<\/p>

1990 y\u0131l\u0131nda yay\u0131nlanan bir \u00e7al\u0131\u015fmada, y\u00fcksek doz biotin’in \u015fiddetli diyabetik periferik n\u00f6ropati \u00fczerindeki etkisi de\u011ferlendirildi. \u00c7al\u0131\u015fmadaki 3 diyabetik hastaya 1-2 y\u0131l boyunca y\u00fcksek doz B7 vitamini verildi. Hem klinik hem de laboratuvar bulgular\u0131 her 3 hastada da belirgin iyile\u015fme g\u00f6sterdi (12)<\/sub><\/strong>.<\/p>

5. B7 Vitamini Cilt Sa\u011fl\u0131\u011f\u0131 i\u00e7in \u00f6nemlidir.<\/h3>

Biotin eksikli\u011fi s\u0131kl\u0131kla cilt konular\u0131nda kendini g\u00f6sterir. Baz\u0131 insanlar bunun sonucunda eksfoliye edici veya eritemli dermatit denilen bir cilt hastal\u0131\u011f\u0131 geli\u015ftirebilir (13)<\/sub><\/strong>.<\/p>

Eksfoliye edici dermatit, ciltteki k\u0131rm\u0131z\u0131 pullu lekeler ile karakterizedir.<\/p>

Biotin genellikle oral yoldan al\u0131nmas\u0131na ra\u011fmen, bir \u00e7al\u0131\u015fma, bir merhem \u015feklinde perk\u00fctan olarak uyguland\u0131\u011f\u0131nda deriden emilme kabiliyetini test etti. \u00c7al\u0131\u015fmaya, atopik dermatitli (egzama) yirmi hasta ve on bir sa\u011fl\u0131kl\u0131 g\u00f6n\u00fcll\u00fc dahil edildi. Biyotin i\u00e7eren merhemin perk\u00fctan uygulanmas\u0131 serum biyotin d\u00fczeylerini \u00f6nemli \u00f6l\u00e7\u00fcde artt\u0131rd\u0131. \u00c7al\u0131\u015fma, biotin’in insan derisi taraf\u0131ndan kolayca absorbe edildi\u011fi sonucuna varm\u0131\u015ft\u0131r (14)<\/sub><\/strong>.<\/p>

B7 vitamini, kemoterapinin neden oldu\u011fu deri d\u00f6k\u00fcnt\u00fcs\u00fc tedavisinde olumlu bir etkiye sahiptir. \u0130ki farkl\u0131 kemoterapi ajan\u0131 ile cilt kanseri tedavisi g\u00f6ren 4 hastan\u0131n yer ald\u0131\u011f\u0131 k\u00fc\u00e7\u00fck bir \u00e7al\u0131\u015fmada, biotin ila\u00e7lar\u0131n yol a\u00e7t\u0131\u011f\u0131 deri d\u00f6k\u00fcnt\u00fcs\u00fcn\u00fc azaltm\u0131\u015ft\u0131r\u00a0(15)<\/sub><\/strong>.<\/p>

6. Vitamini do\u011fu\u015ftan gelen sakatl\u0131klar\u0131 \u00f6nleyebilir.<\/h3>

Baz\u0131 \u00e7al\u0131\u015fmalar biotin eksikli\u011finin hamile kad\u0131nlarda nispeten yayg\u0131n oldu\u011funu g\u00f6stermi\u015ftir (16)<\/sub><\/strong>.<\/p>

Durumdan etkilenen hamile kad\u0131nlar\u0131n oran\u0131 % 50 den y\u00fcksek olabilir (16)<\/sub><\/strong>.<\/p>

Marjinal biotin eksikli\u011fi, ilk trimesterde en y\u00fcksek d\u00fczeydedir ve do\u011fum kusurlar\u0131n\u0131n olas\u0131 geli\u015fimi hakk\u0131nda ciddi endi\u015felere yol a\u00e7maktad\u0131r (17)<\/sub><\/strong>.<\/p>

B7 vitamini eksikli\u011fi yar\u0131k damak olu\u015fumundan k\u0131smen sorumlu gibi g\u00f6r\u00fcnmektedir (18)<\/sub><\/strong>.<\/p>

Yar\u0131k damak kusurunun yan\u0131 s\u0131ra, hayvan \u00e7al\u0131\u015fmalar\u0131 maternal biotin eksikli\u011finin mikromelya ve mikrognati gibi \u00e7e\u015fitli farkl\u0131 anormallikler \u00fcretebilece\u011fini g\u00f6stermi\u015ftir (18)<\/sub><\/strong>.<\/p>

7. B7 Vitamini ba\u011f\u0131\u015f\u0131kl\u0131k fonksiyonunda rol oynar.<\/h3>

Sitokinler, v\u00fccuttaki \u00e7e\u015fitli h\u00fccreler aras\u0131ndaki ileti\u015fimi kolayla\u015ft\u0131ran, kimyasal haberciler gibi davranan k\u00fc\u00e7\u00fck salg\u0131lanm\u0131\u015f proteinlerdir (19)<\/sub><\/strong>.<\/p>

Ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri ile etkile\u015fime girerek v\u00fccudun bakteri ve vir\u00fcslerin neden oldu\u011fu enfeksiyonlara kar\u015f\u0131 tepkisini d\u00fczenler. B7 vitamini takviyesi, insan imm\u00fcn h\u00fccrelerinde gen ekspresyonunu etkileyerek sitokinlerin \u00fcretimini artt\u0131r\u0131r (20)<\/sub><\/strong>.<\/p>

8. B7 Vitamini, Multipl Sklerozu tedavi etme potansiyeline sahip olabilir.<\/h3>

Multipl Skleroz (MS), sinir h\u00fccrelerinde miyelin k\u0131l\u0131f\u0131n\u0131n bozulmas\u0131yla kategorize edilen otoimm\u00fcn bir hastal\u0131kt\u0131r. Sonu\u00e7 olarak, bu sinir h\u00fccreleri bir dizi soruna neden olarak hasar g\u00f6r\u00fcr (21)<\/sub><\/strong>.<\/p>

Bununla birlikte, bir\u00e7ok \u00e7al\u0131\u015fma biyotininin MS hastalar\u0131nda sa\u011fl\u0131k problemlerini iyile\u015ftirmede potansiyel kullan\u0131m\u0131n\u0131 g\u00f6stermektedir. Bir 2015 \u00e7al\u0131\u015fmas\u0131nda y\u00fcksek doz biotin’in 23 MS hastas\u0131 \u00fczerindeki etkileri ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r. Optik sinire ba\u011fl\u0131 g\u00f6rme yetersizli\u011fi olan 4 hasta, iyile\u015fme bildirmi\u015ftir. Omurilik sorunu olan 16 hastan\u0131n da kayda de\u011fer iyile\u015fmeleri vard\u0131.<\/p>

\u00c7al\u0131\u015fma, bu kadar y\u00fcksek dozlarda biotinin hastal\u0131\u011f\u0131n ilerlemesini durdurabilece\u011fi ve bununla ili\u015fkili sakatl\u0131\u011f\u0131 azaltabilece\u011fi sonucuna varm\u0131\u015ft\u0131r (22)<\/sub><\/strong>.<\/p>

2016 y\u0131l\u0131nda yap\u0131lan bir ba\u015fka inceleme ve \u00e7al\u0131\u015fma da benzer sonu\u00e7lara ula\u015fm\u0131\u015ft\u0131r. Ara\u015ft\u0131rmac\u0131lar, y\u00fcksek B7 vitamini dozlar\u0131n\u0131n miyelin \u00fcretimi ve enerji \u00fcretimi yoluyla remiyelinizasyonu sa\u011flad\u0131\u011f\u0131n\u0131 varsay\u0131yorlar. Di\u011fer \u00f6n \u00e7al\u0131\u015fmalar da ayn\u0131 \u015feyi bildirmi\u015ftir. Ancak, daha fazla ara\u015ft\u0131rma bu sonu\u00e7lar\u0131n sa\u011flamla\u015ft\u0131r\u0131lmas\u0131na yard\u0131mc\u0131 olacakt\u0131r (23,24,25)<\/sub><\/strong>.<\/p>

9. B7 Vitamini, ya\u011flar\u0131n, karbonhidratlar\u0131n ve proteinin metabolizmas\u0131 i\u00e7in \u00f6nemlidir.<\/h3>

\u00c7ok say\u0131da \u00e7al\u0131\u015fma, bu makrobesinlerin metabolizmas\u0131nda biotinin rol\u00fcn\u00fcn \u00f6nemini g\u00f6stermektedir. Bu i\u015flemlerde yer alan belirli enzimler, biotinin d\u00fczg\u00fcn \u00e7al\u0131\u015fmas\u0131n\u0131 gerektirir. Ba\u015fka bir deyi\u015fle, v\u00fccudun enerji \u00fcretiminde kritik bir rol oynamaktad\u0131r (26,27)<\/sub><\/strong>.<\/p>

B7 Vitamini Eksikli\u011fi, Belirti ve Bulgular\u0131<\/h2>

Biotin eksikli\u011fi nispeten nadir olmas\u0131na ra\u011fmen, klinik literat\u00fcrde g\u00f6zlemlenmi\u015f ve ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r. Biyotinidaz eksikli\u011fi ad\u0131 verilen nadir g\u00f6r\u00fclen bir genetik biyotin-duyarl\u0131 bozuklu\u011fu olan ki\u015filer, durumun geli\u015fmesi i\u00e7in \u00f6zellikle risk alt\u0131ndad\u0131r (12)<\/sub><\/strong>.<\/p>

Gebe kad\u0131nlarda biotin eksikli\u011fi geli\u015ftirme riski daha y\u00fcksektir.<\/p>

Asl\u0131nda, B7 vitamini eksikli\u011fi laboratuvar ortam\u0131nda s\u0131kl\u0131kla saptanmaz. Sa\u00e7 d\u00f6k\u00fclmesi, deri d\u00f6k\u00fcnt\u00fcleri, depresyon, yorgunluk, hal\u00fcsinasyonlar ve ekstremitelerin kar\u0131ncalanmas\u0131 gibi semptomlar s\u0131kl\u0131kla biotin eksikli\u011finin g\u00f6stergesidir.<\/p>

Biyotinidaz, biyotinin geri d\u00f6n\u00fc\u015f\u00fcm\u00fcnden ve onu diyet kaynaklar\u0131ndan biyolojik olarak kullan\u0131labilir hale getirmesinden sorumlu olan bir enzimdir (28)<\/sub><\/strong>.<\/p>

Biyotinidaz eksikli\u011fi olan ki\u015filerde, olumsuz n\u00f6rolojik sonu\u00e7lardan ka\u00e7\u0131nmak i\u00e7in biotin ile ya\u015fam boyu takviye gerekmektedir (29)<\/sub><\/strong>.<\/p>

Baz\u0131 emziren annelerin s\u00fct\u00fcnde mevcut olan biotin eksikli\u011fi de, s\u0131kl\u0131kla emzirilen bebeklerde biyotin eksikli\u011finin geli\u015fmesine ve seboreik dermatite yol a\u00e7abilir (30)<\/sub><\/strong>.<\/p>

B7 Vitamini Fazlal\u0131\u011f\u0131, Yan Etkileri ve Etkile\u015fimleri<\/h2>

Biotin kan testlerini \u00e7arp\u0131tabilir.<\/h3>

Y\u00fcksek doz B7 vitamini takviyesi tiroid testi sonu\u00e7lar\u0131n\u0131 \u00e7arp\u0131tabilir ve Grave hastal\u0131\u011f\u0131n\u0131n laboratuvar modelini taklit edebilir (31)<\/sub><\/strong>.<\/p>

Biotin, IBS benzeri semptomlara neden olabilir.<\/h3>

\u00c7o\u011fu insan biotin takviyelerini kald\u0131rabilirken, baz\u0131 insanlarda bulant\u0131 ve sindirim sorunlar\u0131 gibi hafif yan etkiler g\u00f6r\u00fclebilir. Biotinle ili\u015fkili bilinen \u00e7ok fazla toksisite belirtisi yoktur.<\/p>

\u00d6nerilen G\u00fcnl\u00fck Biotin Dozu<\/h2>
\u00a0<\/td>KADIN<\/strong><\/td>ERKEK<\/strong><\/td><\/tr>
0-6 ay<\/strong><\/td>5 mcg<\/td>5 mcg<\/td><\/tr>
6-12 ay<\/strong><\/td>6 mcg<\/td>6 mcg<\/td><\/tr>
1-3 ya\u015f<\/strong><\/td>8 mcg<\/td>8 mcg<\/td><\/tr>
4-8 ya\u015f<\/strong><\/td>12\u00a0 mcg<\/td>12 mcg<\/td><\/tr>
9-13 ya\u015f<\/strong><\/td>20 mcg<\/td>20 mcg<\/td><\/tr>
14-18 ya\u015f<\/strong><\/td>25 mcg<\/td>25 mcg<\/td><\/tr>
19-30 ya\u015f<\/strong><\/td>30 mcg<\/td>30 mcg<\/td><\/tr>
31-50 ya\u015f<\/strong><\/td>30 mcg<\/td>30 mcg<\/td><\/tr>
51-70 ya\u015f<\/strong><\/td>30 mcg<\/td>30 mcg<\/td><\/tr>
70 ya\u015f \u00fcst\u00fc<\/strong><\/td>30 mcg<\/td>30 mcg<\/td><\/tr>
Gebelikte<\/strong><\/td>30 mcg<\/td>\u00a0<\/td><\/tr>
Laktasyon<\/strong><\/td>35 mcg<\/td>\u00a0<\/td><\/tr><\/tbody><\/table>

*<\/strong> Food and Nutrition Board, Institute of Medicine, National Academies<\/a>\u00a0g\u00f6re yeti\u015fkinlerde \u00f6nerilen g\u00fcnl\u00fck B7 vitamini<\/b> al\u0131m de\u011feri 30 mcg\u00a0<\/b>olarak belirlenmi\u015ftir.<\/p>

**<\/strong> T.C. Tar\u0131m,G\u0131da ve Hayvanc\u0131l\u0131k Bakanl\u0131\u011f\u0131<\/a>‘na g\u00f6re yeti\u015fkinler i\u00e7in B7 vitamini<\/b> g\u00fcnl\u00fck referans al\u0131m de\u011feri 50 mcg <\/b>olarak belirlenmi\u015ftir.<\/p>

Sonu\u00e7<\/h2>

Biotin normal v\u00fccut fonksiyonu i\u00e7in gerekli olmakla birlikte, takviyeler hamile kad\u0131nlara ve baz\u0131 diyabet hastalar\u0131na yard\u0131mc\u0131 olabilir. Ayr\u0131ca sa\u011fl\u0131kl\u0131 sa\u00e7, cilt veya t\u0131rnaklarla ilgili baz\u0131 \u00e7al\u0131\u015fmalar B7 vitamininin olumlu yararlar\u0131n\u0131 g\u00f6stermektedir.<\/p>

Optimum sa\u011fl\u0131\u011f\u0131n\u0131z i\u00e7in dengeli, sa\u011fl\u0131kl\u0131, i\u015flenmemi\u015f veya asgari d\u00fczeyde i\u015flenmi\u015f g\u0131dalardan olu\u015fan bir diyet yemek her zaman \u00f6nemlidir. Bu ko\u015fullar\u0131 sa\u011flamakta zorluk\u00a0 \u00e7ekiyorsan\u0131z veya bir B7 vitamini eksikli\u011fine sahipseniz, takviyeler bir \u00e7\u00f6z\u00fcm olabilir. Bir biotin takviyesi kullanmadan doktorunuza dan\u0131\u015fman\u0131z \u00f6nemlidir.<\/p>

Imucore<\/strong>24<\/strong>, i\u00e7eri\u011finde (10 ml’sinde)\u00a050 mcg B7 vitamini <\/b>deste\u011fi ile g\u00fcnl\u00fck ihtiyac\u0131n\u0131z\u0131n % 100 \u00fcn\u00fc<\/strong> kar\u015f\u0131layarak, beslenme program\u0131n\u0131za g\u00fc\u00e7l\u00fc bir katk\u0131da bulunur.(**<\/strong><\/a>)<\/h4>

Kan\u0131ta dayal\u0131 31 ayr\u0131 kaynaktan derlenmi\u015ftir.<\/a><\/p>

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(High Doses of Biotin) in Progressive Multiple Sclerosis: Results of a Pivotal Phase III Randomized Double Blind Placebo Controlled Study (PL2.002)<\/strong> \/  https:\/\/n.neurology.org\/content\/84\/14_Supplement\/PL2.002\n26.<\/strong> The Journal of Nutrition, Volume 104, Issue 3, March 1974, Pages 315\u2013322,\/ Effect of Dietary Biotin and Lipid on Growth, Stamina, Lipid Metabolism and Biotin-containing Enzymes in Brook Trout (Salvelinus fontinalis)<\/strong> \/ https:\/\/academic.oup.com\/jn\/article-abstract\/104\/3\/315\/4776058\n27.<\/strong> Biochemistry of Biotin<\/strong> \/ https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0083672908603350\n28.<\/strong> Clin Chim Acta. 1996 Nov 15 \/ Biotinidase and its roles in biotin metabolism.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8930409\n29.<\/strong> Genet Med. 2012 Jun \/ Biotinidase deficiency: \"if you have to have an inherited metabolic disease, this is the one to have\"<\/strong>.\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22241090\n30.<\/strong> Pediatrics. 1969 Dec \/ Seborrheic dermatitis of infants: treatment with biotin injections for the nursing mother.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/4243742\n31.<\/strong> Biotin Treatment Mimicking Graves\u2019 Disease<\/strong> \/ https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc1602096#t=article<\/pre><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"
B7 Vitamininin Yararlar\u0131, Eksikli\u011fi, Fazlal\u0131\u011f\u0131 ve Daha Fazlas\u0131 H vitamini yada Biotin olarak da bilinen B7 vitamini, v\u00fccudun g\u0131dalar\u0131 enerjiye d\u00f6n\u00fc\u015ft\u00fcrmesine yard\u0131mc\u0131 olan B kompleks vitaminlerinden biridir . \u201cBiotin\u201d kelimesi, \u201cya\u015fam\u201d veya \u201cdevam\u201d anlam\u0131na gelen eski Yunanca \u201cbiotos\u201d kelimesinden gelir. B vitaminleri ve \u00f6zellikle biotin, cildinizin, sa\u00e7\u0131n\u0131z\u0131n, g\u00f6zlerinizin, karaci\u011ferinizin ve sinir sisteminizin sa\u011fl\u0131kl\u0131 kalmas\u0131na yard\u0131mc\u0131 … Continue reading B7 Vitamini ve \u00d6zellikleri<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":8440,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[125],"tags":[],"_links":{"self":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts\/292"}],"collection":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/comments?post=292"}],"version-history":[{"count":1,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts\/292\/revisions"}],"predecessor-version":[{"id":8441,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts\/292\/revisions\/8441"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/media\/8440"}],"wp:attachment":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/media?parent=292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/categories?post=292"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/tags?post=292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}