{"id":326,"date":"2020-05-04T13:03:45","date_gmt":"2020-05-04T10:03:45","guid":{"rendered":"https:\/\/www.imucore24.com\/?page_id=326"},"modified":"2020-05-10T12:48:11","modified_gmt":"2020-05-10T09:48:11","slug":"selenyum-ozellikleri","status":"publish","type":"post","link":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/selenyum-ozellikleri\/","title":{"rendered":"Selenyum ve \u00d6zellikleri"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"326\" class=\"elementor elementor-326\" data-elementor-settings=\"[]\">\n\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section class=\"elementor-element elementor-element-788c8cb8 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-section elementor-top-section\" data-id=\"788c8cb8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cb1f79c elementor-column elementor-col-100 elementor-top-column\" data-id=\"cb1f79c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap  elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t<div class=\"elementor-element elementor-element-41603d13 elementor-widget elementor-widget-text-editor\" data-id=\"41603d13\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\"><h1>Selenyumun Yararlar\u0131, Eksikli\u011fi, Fazlal\u0131\u011f\u0131 ve Daha Fazlas\u0131<\/h1><h4>G\u00fcn\u00fcm\u00fczde ad\u0131 ve etkileri yeni yeni bilinmeye ba\u015flayan Selenyum, sa\u011fl\u0131\u011f\u0131n\u0131z i\u00e7in \u00e7ok \u00f6nemlidir.<\/h4><h4>Selenyum esansiyel bir mineraldir ve v\u00fccudunuz taraf\u0131ndan \u00fcretilemez. Bu y\u00fczden besinler yoluyla al\u0131nmas\u0131 gerekir.<\/h4><h4>Sadece k\u00fc\u00e7\u00fck miktarlarda gereklidir ancak metabolizman\u0131z ve tiroid fonksiyonunuz da dahil olmak \u00fczere v\u00fccudunuzda ki bir\u00e7ok s\u00fcre\u00e7te \u00f6nemli bir rol oynar.<\/h4><h4>Bu makalede selenyumun yararlar\u0131, eksikli\u011fi veya fazlal\u0131\u011f\u0131 ve buna ba\u011fl\u0131 yan etkileri incelenmi\u015ftir.<\/h4><h2>Selenyum nedir?<\/h2><p>Selenyum, bili\u015fsel i\u015flev, sa\u011fl\u0131kl\u0131 bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemi ve hem erkek hem de kad\u0131nlarda do\u011furganl\u0131k dahil olmak \u00fczere, bir\u00e7ok v\u00fccut s\u00fcre\u00e7leri i\u00e7in \u00f6nemli olan \u00f6nemli bir eser mineraldir.<br \/>Tiroid hormon metabolizmas\u0131na ve DNA sentezine katk\u0131da bulunur, oksidatif hasar ve enfeksiyonlara kar\u015f\u0131 korumaya yard\u0131mc\u0131 olur.<\/p><p>\u0130nsan dokusunda, \u00e7o\u011funlukla iskelet kas\u0131nda bulunur.<\/p><p>Diyet kaynaklar\u0131 de\u011fi\u015fkendir. Brezilya f\u0131st\u0131\u011f\u0131, deniz \u00fcr\u00fcnleri,etler, f\u0131nd\u0131k ve yumurtalar iyi birer kayna\u011f\u0131d\u0131r. <strong><sub>(33,34,35)<\/sub><\/strong><\/p><p>G\u0131dadaki selenyumun miktar\u0131 genellikle g\u0131dan\u0131n yeti\u015ftirdi\u011fi toprak ve suyun selenyum konsantrasyonuna ba\u011fl\u0131d\u0131r.<\/p><h2>Selenyumun \u0130\u015flevleri ve Yararlar\u0131<\/h2><h3>1. G\u00fc\u00e7l\u00fc bir antioksidan g\u00f6revi g\u00f6r\u00fcr.<\/h3><p>Antioksidanlar, serbest radikallerin neden oldu\u011fu h\u00fccre hasar\u0131n\u0131 \u00f6nleyen g\u0131dalardaki bile\u015fiklerdir.<\/p><p>Serbest radikaller g\u00fcnl\u00fck olarak v\u00fccudunuzda olu\u015fan metabolizma gibi i\u015flemlerin yan \u00fcr\u00fcnleridir.\u00a0<\/p><p>Genellikle k\u00f6t\u00fc etkileri vard\u0131r, ancak serbest radikallerin sa\u011fl\u0131\u011f\u0131n\u0131z i\u00e7in esast\u0131r. V\u00fccudunuzu hastal\u0131ktan korumak da dahil olmak \u00fczere \u00f6nemli i\u015flevleri yerine getirirler.<\/p><p>Bununla birlikte, sigara i\u00e7me, alkol kullan\u0131m\u0131 ve stres gibi durumlar a\u015f\u0131r\u0131 serbest radikallere neden olabilir. Bu, sa\u011fl\u0131kl\u0131 h\u00fccrelere zarar veren oksidatif strese yol a\u00e7ar. <strong><sub>(1)<\/sub><\/strong><\/p><p>Oksidatif stres, kalp hastal\u0131\u011f\u0131, Alzheimer ve kanser gibi kronik durumlarla ve ayr\u0131ca erken ya\u015flanma ve inme riski ile ili\u015fkilendirilmi\u015ftir. <strong><sub>(2,3,4,5,6)<\/sub><\/strong><\/p><p>Selenyum gibi antioksidanlar, serbest radikal say\u0131lar\u0131 kontrol alt\u0131nda tutarak oksidatif stresi azaltmaya yard\u0131mc\u0131 olur. <strong><sub>(7)<\/sub><\/strong><\/p><p>A\u015f\u0131r\u0131 serbest radikalleri n\u00f6tralize ederek ve oksidatif stresin neden oldu\u011fu zararlardan koruyarak \u00e7al\u0131\u015f\u0131rlar.<\/p><blockquote><p>Selenyum oksidatif stresle sava\u015fan ve v\u00fccudunuzu kalp hastal\u0131\u011f\u0131 ve kanser gibi kronik durumlardan koruman\u0131za yard\u0131mc\u0131 olan g\u00fc\u00e7l\u00fc bir antioksidand\u0131r.<\/p><\/blockquote><h3>2. Baz\u0131 kanser risklerini azaltabilir.<\/h3><p>Oksidatif stresi azaltmaya ek olarak, selenyumun baz\u0131 kanser risklerini azaltmada yard\u0131mc\u0131 etkileri olabilir.<\/p><p>Bu durum, selenyumun DNA hasar\u0131n\u0131 ve oksidatif stresi azaltma, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminizi g\u00fc\u00e7lendirme ve kanser h\u00fccrelerini tahrip etme yetene\u011fine ba\u011flanm\u0131\u015ft\u0131r. <strong><sub>(8)<\/sub><\/strong><\/p><p>350.000&#8217;den fazla ki\u015fiyi i\u00e7eren 69 \u00e7al\u0131\u015fman\u0131n incelenmesi, kanda y\u00fcksek bir selenyum seviyesine sahip olman\u0131n meme, akci\u011fer, kolon ve prostat kanserleri de dahil olmak \u00fczere baz\u0131 kanser t\u00fcrlerinde risk ile ili\u015fkili oldu\u011funu buldu. <strong><sub>(9)<\/sub><\/strong><\/p><p>Bununla birlikte, baz\u0131 ara\u015ft\u0131rmalar selenyumla takviyenin radyasyon tedavisi alan insanlarda yan etkileri azaltabilece\u011fini \u00f6ne s\u00fcrmektedir.<\/p><ul><li>\u00d6rne\u011fin, bir \u00e7al\u0131\u015fma selenyumun oral takviyelerinin servikal ve uterin kanserli kad\u0131nlarda genel ya\u015fam kalitesini iyile\u015ftirdi\u011fini ve radyasyona ba\u011fl\u0131 ishali azaltt\u0131\u011f\u0131n\u0131 buldu. <strong><sub>(10)<\/sub><\/strong><\/li><\/ul><blockquote><p>Y\u00fcksek selenyum kan seviyeleri, baz\u0131 kanserlere kar\u015f\u0131 koruma sa\u011flayabilir. Selenyumla takviye etmek, radyasyon tedavisi g\u00f6ren ki\u015filerde ya\u015fam kalitesini y\u00fckseltmeye yard\u0131mc\u0131 olabilir.<\/p><\/blockquote><h3>3. Kalp hastal\u0131klar\u0131na kar\u015f\u0131 koruyabilir.<\/h3><p>Selenyumdan zengin bir diyetle selenyumun seviyelerinin artmas\u0131 kalp hastal\u0131\u011f\u0131 riskiyle ili\u015fkilendirildi\u011finden, kalbinizin sa\u011fl\u0131kl\u0131 kalmas\u0131na yard\u0131mc\u0131 olabilir.<\/p><ul><li>25 g\u00f6zlem \u00e7al\u0131\u015fmas\u0131n\u0131n analizinde kan selenyum seviyelerinde % 50 art\u0131\u015f, kalp hastal\u0131\u011f\u0131 riskinde % 24 azalma ile ili\u015fkilendirilmi\u015ftir. <strong><sub>(11)<\/sub><\/strong><\/li><\/ul><ul><li>Ayr\u0131ca, kalp hastal\u0131\u011f\u0131 olan 433.000&#8217;den fazla ki\u015fiyi i\u00e7eren 16 kontroll\u00fc \u00e7al\u0131\u015fman\u0131n incelenmesi, selenyumlu takviye alman\u0131n inflamatuar belirte\u00e7 olan C-reaktif protein (CRP) seviyelerini d\u00fc\u015f\u00fcrd\u00fc\u011f\u00fcn\u00fc g\u00f6stermi\u015ftir. Bununla birlikte, g\u00fc\u00e7l\u00fc bir antioksidan olan glutatyon peroksidaz seviyelerini artt\u0131rm\u0131\u015ft\u0131r. <strong><sub>(12)<\/sub><\/strong><\/li><\/ul><p>Bu, selenyumun v\u00fccudunuzdaki iltihab\u0131 ve oksidatif stresi azaltarak kalp hastal\u0131\u011f\u0131 riskini azaltmaya yard\u0131mc\u0131 olabilece\u011fini g\u00f6sterir. Oksidatif stres ve inflamasyon ateroskleroz veya arterlerde plak birikimi ile ili\u015fkilendirilmi\u015ftir.<\/p><p>Ateroskleroz, fel\u00e7, kalp krizi ve kalp hastal\u0131\u011f\u0131 gibi tehlikeli sa\u011fl\u0131k sorunlar\u0131na yol a\u00e7abilir <strong><sub>(13)<\/sub><\/strong><\/p><p>Selenyum bak\u0131m\u0131ndan zengin yiyecekleri diyetinize dahil etmek, oksidatif stres ve iltihap seviyelerini minimumda tutmak i\u00e7in etkili bir yoldur.<\/p><blockquote><p>Selenyum, oksidatif stresi kontrol alt\u0131nda tutarak ve kalp hastal\u0131\u011f\u0131 riskinizi azaltarak kalbinizin sa\u011fl\u0131kl\u0131 kalmas\u0131na yard\u0131mc\u0131 olabilir.<\/p><\/blockquote><h3>4. Zihinsel d\u00fc\u015f\u00fc\u015f\u00fc \u00f6nlemeye yard\u0131mc\u0131 olur.<\/h3><p>Alzheimer hastal\u0131\u011f\u0131 haf\u0131za kayb\u0131na neden olan, d\u00fc\u015f\u00fcnme ve davran\u0131\u015flar\u0131 olumsuz y\u00f6nde etkileyen y\u0131k\u0131c\u0131 bir durumdur.\u00a0<\/p><p>Oksidatif stresin, Parkinson, multipl skleroz ve Alzheimer gibi n\u00f6rolojik hastal\u0131klar\u0131n hem ba\u015flang\u0131c\u0131nda hem de ilerlemesinde rol oynad\u0131\u011f\u0131na inan\u0131lmaktad\u0131r. <strong><sub>(14)<\/sub><\/strong><\/p><p>Baz\u0131 \u00e7al\u0131\u015fmalar Alzheimer hastal\u0131\u011f\u0131 olan hastalar\u0131n kanda selenyum seviyelerinin d\u00fc\u015f\u00fck oldu\u011funu g\u00f6stermi\u015ftir. <strong><sub>(15,16)<\/sub><\/strong><\/p><p>Bununla birlikte, baz\u0131 \u00e7al\u0131\u015fmalar hem g\u0131dalardaki hem de takviyelerdeki antioksidanlar\u0131n Alzheimer hastalar\u0131nda haf\u0131zay\u0131 geli\u015ftirebilece\u011fini bulmu\u015ftur. <strong><sub>(17)<\/sub><\/strong><\/p><p>K\u00fc\u00e7\u00fck bir \u00e7al\u0131\u015fma, g\u00fcnde bir \u00f6\u011f\u00fcn\u00fcn selenyum y\u00f6n\u00fcnden zengin Brezilya f\u0131st\u0131\u011f\u0131 ile takviye edilmesinin, hafif bili\u015fsel bozuklu\u011fu olan hastalarda s\u00f6zel ak\u0131c\u0131l\u0131\u011f\u0131 ve di\u011fer zihinsel i\u015flevleri iyile\u015ftirdi\u011fini buldu. <strong><sub>(18)<\/sub><\/strong><\/p><p>Dahas\u0131, deniz \u00fcr\u00fcnleri ve f\u0131nd\u0131k gibi y\u00fcksek selenyumlu yiyecekler bak\u0131m\u0131ndan zengin olan Akdeniz diyeti, Alzheimer hastal\u0131\u011f\u0131na yakalanma riskini d\u00fc\u015f\u00fcr\u00fcr. <strong><sub>(19,20)<\/sub><\/strong><\/p><blockquote><p>Selenyum y\u00f6n\u00fcnden zengin bir diyet, Alzheimer hastal\u0131\u011f\u0131 olan ki\u015filerde zihinsel d\u00fc\u015f\u00fc\u015f\u00fcn \u00f6nlenmesine ve haf\u0131za kayb\u0131n\u0131n iyile\u015ftirilmesine yard\u0131mc\u0131 olabilir.<\/p><\/blockquote><h3>5. Tiroid sa\u011fl\u0131\u011f\u0131 i\u00e7in \u00f6nemlidir.<\/h3><p>Selenyum tiroid bezinizin d\u00fczg\u00fcn \u00e7al\u0131\u015fmas\u0131 i\u00e7in \u00f6nemlidir. Asl\u0131nda, tiroid dokusu insan v\u00fccudundaki di\u011fer herhangi bir organdan daha fazla selenyum i\u00e7erir. <strong><sub>(21)<\/sub><\/strong><\/p><p>Bu g\u00fc\u00e7l\u00fc mineral, tiroidin oksidatif hasara kar\u015f\u0131 korunmas\u0131na yard\u0131mc\u0131 olur ve tiroid hormonlar\u0131n\u0131n \u00fcretiminde \u00f6nemli bir rol oynar.<\/p><p>Metabolizman\u0131z\u0131 d\u00fczenleyerek b\u00fcy\u00fcme ve geli\u015fmeyi kontrol etti\u011fi i\u00e7in sa\u011fl\u0131kl\u0131 bir tiroid bezi \u00f6nemlidir. <strong><sub>(22)<\/sub><\/strong><\/p><p>Selenyumun eksikli\u011fi, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin tiroid bezine sald\u0131rd\u0131\u011f\u0131 bir t\u00fcr hipotiroidizm olan Hashimoto tiroiditi gibi tiroid ko\u015fullar\u0131yla ili\u015fkilendirilmi\u015ftir.<\/p><ul><li>6.000&#8217;den fazla ki\u015fiyi i\u00e7eren g\u00f6zlemsel bir \u00e7al\u0131\u015fma, selenyumun d\u00fc\u015f\u00fck seviyelerinin, otoimm\u00fcn tiroidit ve hipotiroidizm riskinde art\u0131\u015f ile ili\u015fkili oldu\u011funu bulmu\u015ftur. <strong><sub>(23)<\/sub><\/strong><\/li><\/ul><p>Ek olarak, baz\u0131 \u00e7al\u0131\u015fmalar selenyumla takviyenin Hashimoto hastal\u0131\u011f\u0131 olan insanlara fayda sa\u011flayabilece\u011fini g\u00f6stermi\u015ftir.<\/p><ul><li>Bir g\u00f6zden ge\u00e7irme, \u00fc\u00e7 ay boyunca g\u00fcnl\u00fck selenyum takviyesi alman\u0131n daha d\u00fc\u015f\u00fck tiroid antikorlar\u0131 ile sonu\u00e7land\u0131\u011f\u0131 sonucuna varm\u0131\u015ft\u0131r. Ayn\u0131 zamanda Hashimoto hastal\u0131\u011f\u0131 olanlarda ruh hali ve genel iyilik halinde iyile\u015fmelere yol a\u00e7m\u0131\u015ft\u0131r. <strong><sub>(24)<\/sub><\/strong><\/li><\/ul><blockquote><p>Selenyum tiroid bezini oksidatif strese kar\u015f\u0131 korur ve tiroid hormonu \u00fcretimi i\u00e7in gereklidir. Hashimoto hastal\u0131\u011f\u0131na ve di\u011fer tiroid hastal\u0131\u011f\u0131na sahip insanlara yard\u0131m edebilir, ancak daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 vard\u0131r.<\/p><\/blockquote><h3>6. Ba\u011f\u0131\u015f\u0131kl\u0131k sisteminizi g\u00fc\u00e7lendirir.<\/h3><p>Ba\u011f\u0131\u015f\u0131kl\u0131k sisteminiz, potansiyel tehditleri tan\u0131mlayarak ve bunlarla sava\u015farak v\u00fccudunuzu sa\u011fl\u0131kl\u0131 tutar. Bunlar bakteri, vir\u00fcs ve parazitleri i\u00e7erir.<\/p><p>Selenyum, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminizin sa\u011fl\u0131\u011f\u0131nda \u00f6nemli bir rol oynar. Bu antioksidan v\u00fccudunuzdaki oksidatif stresi azaltmaya yard\u0131mc\u0131 olur, bu da iltihab\u0131 azalt\u0131r ve ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 artt\u0131r\u0131r.<\/p><p>\u00c7al\u0131\u015fmalar, selenyumun kan seviyelerinin artmas\u0131n\u0131n, ba\u011f\u0131\u015f\u0131kl\u0131k tepkisi ile ili\u015fkili oldu\u011funu g\u00f6stermi\u015ftir.<\/p><p>\u00d6te yandan, eksikli\u011fin imm\u00fcn h\u00fccre fonksiyonuna zarar verdi\u011fi ve daha yava\u015f bir imm\u00fcn tepkiye yol a\u00e7abilece\u011fi g\u00f6sterilmi\u015ftir. <strong><sub>(25)<\/sub><\/strong><\/p><p>\u00c7al\u0131\u015fmalar, HIV&#8217;li ki\u015filerde artan \u00f6l\u00fcm ve hastal\u0131k ilerlemesi riskini de beraberinde getirmi\u015f olan eksiklik ile ili\u015fkiliyken, takviyelerin daha az hastaneye yatmaya ve bu hastalarda semptomlarda iyile\u015fmeye yol a\u00e7t\u0131\u011f\u0131 g\u00f6sterilmi\u015ftir. <strong><sub>(26)<\/sub><\/strong><\/p><p>Bununla birlikte, selenyumla takviye, grip, t\u00fcberk\u00fcloz ve hepatit C hastalar\u0131nda ba\u011f\u0131\u015f\u0131kl\u0131k sistemini g\u00fc\u00e7lendirmeye yard\u0131mc\u0131 olabilir. <strong><sub>(27)<\/sub><\/strong><\/p><blockquote><p>Selenyum, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminizin sa\u011fl\u0131\u011f\u0131 ve d\u00fczg\u00fcn \u00e7al\u0131\u015fmas\u0131 i\u00e7in \u00e7ok \u00f6nemlidir. Selenyum seviyelerinin y\u00fcksek olmas\u0131, HIV, grip, t\u00fcberk\u00fcloz ve hepatit C&#8217;li ki\u015filerin ba\u011f\u0131\u015f\u0131kl\u0131k sistemlerinin g\u00fc\u00e7lendirilmesine yard\u0131mc\u0131 olabilir.<\/p><\/blockquote><h3>7. Ast\u0131m semptomlar\u0131n\u0131 azaltmaya yard\u0131mc\u0131 olabilir.<\/h3><p>Ast\u0131m, akci\u011ferlerin i\u00e7ine ve d\u0131\u015f\u0131na hava ta\u015f\u0131yan havayollar\u0131n\u0131 etkileyen kronik bir hastal\u0131kt\u0131r.<\/p><p>Bu durumda solunum yollar\u0131 iltihaplan\u0131r ve daralmaya ba\u015flar; h\u0131r\u0131lt\u0131, nefes darl\u0131\u011f\u0131, g\u00f6\u011f\u00fcste s\u0131k\u0131\u015fma ve \u00f6ks\u00fcr\u00fck gibi semptomlara neden olur. <strong><sub>(28)<\/sub><\/strong><\/p><p>Ast\u0131m, v\u00fccutta artan oksidatif stres ve inflamasyon d\u00fczeyleriyle ili\u015fkilendirilmi\u015ftir. <strong><sub>(29)<\/sub><\/strong><\/p><p>Selenyumun iltihab\u0131 azaltma kabiliyeti nedeniyle, baz\u0131 \u00e7al\u0131\u015fmalar bu mineralin ast\u0131mla ili\u015fkili semptomlar\u0131 azaltmaya yard\u0131mc\u0131 olabilece\u011fini g\u00f6stermektedir.<\/p><p>Ara\u015ft\u0131rmalar ast\u0131m\u0131 olan ki\u015filerin kanda selenyum seviyelerinin d\u00fc\u015f\u00fck oldu\u011funu g\u00f6steriyor.<\/p><p>Asl\u0131nda, bir \u00e7al\u0131\u015fmada, kan selenyum d\u00fczeyi y\u00fcksek olan ast\u0131ml\u0131 hastalar\u0131n, d\u00fczeyi d\u00fc\u015f\u00fck olanlara g\u00f6re daha iyi akci\u011fer i\u015flevi oldu\u011fu g\u00f6sterilmi\u015ftir. <strong><sub>(30)<\/sub><\/strong><\/p><p>Selenyum takviyeleri, ast\u0131mla ili\u015fkili semptomlar\u0131n azalt\u0131lmas\u0131na da yard\u0131mc\u0131 olabilir.<\/p><p>\u00d6rne\u011fin, bir \u00e7al\u0131\u015fma, ast\u0131m hastalar\u0131na g\u00fcnde 200 mcg selenyum vermenin, semptomlar\u0131 kontrol etmek i\u00e7in kullan\u0131lan kortikosteroid ila\u00e7lar\u0131n\u0131n kullan\u0131mlar\u0131n\u0131 azaltt\u0131\u011f\u0131n\u0131 buldu. <strong><sub>(31)<\/sub><\/strong><\/p><blockquote><p>Selenyum, v\u00fccuttaki iltihab\u0131 azaltma kabiliyeti nedeniyle ast\u0131m\u0131 olan ki\u015filer i\u00e7in faydal\u0131 olabilir. Ancak, daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 var. <strong><sub>(32)<\/sub><\/strong><\/p><\/blockquote><h2>Selenyum Eksikli\u011fi, Belirti ve Bulgular\u0131<\/h2><p>Selenyum eksikli\u011fi bir dizi belirtiye neden olabilir. En yayg\u0131n olanlar\u0131:<\/p><ul><li>Erkeklerde ve kad\u0131nlarda k\u0131s\u0131rl\u0131k,<\/li><li>Kas G\u00fc\u00e7s\u00fczl\u00fc\u011f\u00fc,<\/li><li>Yorgunluk,<\/li><li>Zihinsel sis,<\/li><li>Sa\u00e7 kayb\u0131,<\/li><li>Zay\u0131f ba\u011f\u0131\u015f\u0131kl\u0131k sistemi<\/li><\/ul><p>Toprakta selenyumun d\u00fc\u015f\u00fck oldu\u011fu bir b\u00f6lgede ya\u015faman\u0131n yan\u0131 s\u0131ra, a\u015fa\u011f\u0131dakiler de ya\u015fad\u0131\u011f\u0131n\u0131z yerden ba\u011f\u0131ms\u0131z olarak bu mineralin eksik riskinizi art\u0131rabilir:<\/p><ul><li>diyaliz tedavisi,<\/li><li>HIV hastalar\u0131,<\/li><li>Crohn hastal\u0131\u011f\u0131 gibi sindirim bozuklu\u011fu olanlar,<\/li><\/ul><p>Bunlar\u0131n her biri, diyetinizle yeterince selenyum alsan\u0131z bile, v\u00fccudunuzda selenyumun emilimini etkileyebilir.<\/p><p>Yeterli selenyum seviyeleri, \u00f6zellikle a\u015fa\u011f\u0131dakiler gibi baz\u0131 gruplar i\u00e7in \u00f6nemlidir:<\/p><ul><li>Graves hastal\u0131\u011f\u0131 gibi tiroid hastal\u0131klar\u0131 olanlar,<\/li><li>Tiroid nod\u00fclleri olanlar,<\/li><li>Kanser hastalar\u0131,<\/li><li>Ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131flam\u0131\u015f olanlar,<\/li><li>Hamileler<\/li><\/ul><p>Selenyumun eksikli\u011fini doktorlar\u0131n te\u015fhis etmesi zor olabilir. Bunun nedeni, yayg\u0131n olarak test edebilecek bir test olmamas\u0131d\u0131r. Baz\u0131 durumlarda, doktorunuz glutatyon peroksidaz seviyenizi \u00f6l\u00e7ebilir. Bu, \u00e7al\u0131\u015fmas\u0131 i\u00e7in selenyum gerektiren bir enzimdir ve seviyesi d\u00fc\u015f\u00fckse, yeterli selenyumunuz olmayabilir.<\/p><h2>Selenyum Fazlal\u0131\u011f\u0131, Yan Etkileri ve Etkile\u015fimleri<\/h2><p>Selenyum sa\u011fl\u0131k i\u00e7in gerekli olsa da, \u00e7ok fazla almak tehlikeli olabilir. Asl\u0131nda, selenyumu y\u00fcksek dozlarda t\u00fcketmek toksik ve hatta \u00f6l\u00fcmc\u00fcl olabilir.<\/p><p>Selenyumun toksisitesi nadir olmakla birlikte, g\u00fcnde 55 mcg \u00f6nerilen miktara yak\u0131n kalmak ve asla g\u00fcnl\u00fck 400 mcg tolere edilebilir \u00fcst s\u0131n\u0131r\u0131 a\u015fmamak \u00f6nemlidir. <strong><sub>(36)<\/sub><\/strong><\/p><p>Selenyum toksisitesinin i\u015faretleri \u015funlard\u0131r:<\/p><ul><li>Sa\u00e7 kayb\u0131,<\/li><li>Ba\u015f d\u00f6nmesi,<\/li><li>Mide bulant\u0131s\u0131,<\/li><li>Kusma,<\/li><li>Y\u00fcz k\u0131zarmas\u0131,<\/li><li>Titreme,<\/li><li>Kas a\u011fr\u0131s\u0131,<\/li><\/ul><p>A\u011f\u0131r vakalarda, akut selenyum toksisitesi ciddi ba\u011f\u0131rsak ve n\u00f6rolojik semptomlara, kalp krizine, b\u00f6brek yetmezli\u011fine ve \u00f6l\u00fcme neden olabilir. <strong><sub>(37)<\/sub><\/strong><\/p><h2>\u00d6nerilen G\u00fcnl\u00fck Selenyum Dozu<\/h2><table><tbody><tr><td width=\"70\">\u00a0<\/td><td width=\"76\"><strong>KADIN<\/strong><\/td><td width=\"76\"><strong>ERKEK<\/strong><\/td><\/tr><tr><td width=\"70\"><strong>0-6 ay<\/strong><\/td><td width=\"76\">15 mcg<\/td><td width=\"76\">15 mcg<\/td><\/tr><tr><td width=\"70\"><strong>6-12 ay<\/strong><\/td><td width=\"76\">20 mcg<\/td><td width=\"76\">20 mcg<\/td><\/tr><tr><td width=\"70\"><strong>1-3 ya\u015f<\/strong><\/td><td width=\"76\">20 mcg<\/td><td width=\"76\">20 mcg<\/td><\/tr><tr><td width=\"70\"><strong>4-8 ya\u015f<\/strong><\/td><td width=\"76\">30 mcg<\/td><td width=\"76\">\u00a030 mcg<\/td><\/tr><tr><td width=\"70\"><strong>9-13 ya\u015f<\/strong><\/td><td width=\"76\">40 mcg<\/td><td width=\"76\">40 mcg<\/td><\/tr><tr><td width=\"70\"><strong>14-18 ya\u015f<\/strong><\/td><td width=\"76\">55 mcg<\/td><td width=\"76\">55 mcg<\/td><\/tr><tr><td width=\"70\"><strong>19-30 ya\u015f<\/strong><\/td><td width=\"76\">55 mcg<\/td><td width=\"76\">55 mcg<\/td><\/tr><tr><td width=\"70\"><strong>31-50 ya\u015f<\/strong><\/td><td width=\"76\">55 mcg<\/td><td width=\"76\">55 mcg<\/td><\/tr><tr><td width=\"70\"><strong>51-70 ya\u015f<\/strong><\/td><td width=\"76\">55 mcg<\/td><td width=\"76\">55 mcg<\/td><\/tr><tr><td width=\"70\"><strong>70 ya\u015f \u00fcst\u00fc<\/strong><\/td><td width=\"76\">55 mcg<\/td><td width=\"76\">55 mcg<\/td><\/tr><tr><td width=\"70\"><strong>Gebelikte<\/strong><\/td><td width=\"76\">60 mcg<\/td><td width=\"76\">\u00a0<\/td><\/tr><tr><td width=\"70\"><strong>Laktasyon<\/strong><\/td><td width=\"76\">70 mcg<\/td><td width=\"76\">\u00a0<\/td><\/tr><\/tbody><\/table><p><strong>*<\/strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK56068\/table\/summarytables.t3\/?report=objectonly\" target=\"_blank\" rel=\"noopener noreferrer\"> Food and Nutrition Board, Institute of Medicine, National Academies<\/a>\u00a0g\u00f6re yeti\u015fkinler i\u00e7in g\u00fcnl\u00fck \u00f6nerilen selenyum minerali al\u0131m de\u011feri <b>55 mcg<\/b> olarak belirlenmi\u015ftir<\/p><p><strong>**<\/strong> <a href=\"http:\/\/www.resmigazete.gov.tr\/eskiler\/2017\/01\/20170126M1-6-1.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">T.C. Tar\u0131m,G\u0131da ve Hayvanc\u0131l\u0131k Bakanl\u0131\u011f\u0131<\/a>&#8216;na g\u00f6re yeti\u015fkinler i\u00e7in selenyum minerali g\u00fcnl\u00fck referans al\u0131m de\u011feri <b>55 mcg <\/b>olarak belirlenmi\u015ftir.<\/p><h4><strong>Imucore<\/strong><strong>24<\/strong>, i\u00e7eri\u011finde (10ml&#8217;sinde)<b> 55 mcg Selenyum <\/b>deste\u011fi ile g\u00fcnl\u00fck ihtiyac\u0131n\u0131z\u0131n <strong>% 100 \u00fcn\u00fc<\/strong>\u00a0kar\u015f\u0131layarak, beslenme program\u0131n\u0131za g\u00fc\u00e7l\u00fc bir katk\u0131da bulunur. (<a href=\"https:\/\/www.imucore24.com\/selenyum\/#BRD\" target=\"_blank\" rel=\"noopener\"><strong>**<\/strong><\/a>)<\/h4><p><a>Kan\u0131ta dayal\u0131 37 ayr\u0131 kaynaktan derlenmi\u015ftir.<\/a><\/p><pre><strong>1.<\/strong> Int J Biomed Sci. 2008 Jun \/ <strong>Free Radicals, Antioxidants in Disease and Health<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3614697\/\n<strong>2.<\/strong> Oxid Med Cell Longev. 2009 \/ <strong>Oxidative stress as a mediator of cardiovascular disease<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2835914\/\n<strong>3.<\/strong> Antioxid Redox Signal. 2006 Nov-Dec \/ <strong>DNA oxidation in Alzheimer's disease.<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17034348\n<strong>4.<\/strong> <strong>The Role of Oxidative Stress in Carcinogenesis<\/strong> \/ https:\/\/www.annualreviews.org\/doi\/full\/10.1146\/annurev.pharmtox.44.101802.121851\n<strong>5.<\/strong> J Signal Transduct.\/ <strong>Oxidative Stress, Mitochondrial Dysfunction, and Aging<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3184498\/\n<strong>6.<\/strong> Antioxidants (Basel). 2014 Sep \/ <strong>Oxidative Stress and the Use of Antioxidants in Stroke<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4665418\/\n<strong>7.<\/strong> Am Heart J. 2008 Dec \/<strong>Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19033020\n<strong>8.<\/strong> Radiat Oncol. 2014; 9: 125.\/ <strong>Updates on clinical studies of selenium supplementation in radiotherapy<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4073179\/\n<strong>9.<\/strong> Sci Rep. 2016 \/<strong>Selenium Exposure and Cancer Risk: an Updated Meta-analysis and Meta-regression<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4726178\/\n<strong>10. <\/strong>Int J Radiat Oncol Biol Phys. 2010 Nov 1 \/ <strong>Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20133068\/\n<strong>11.<\/strong> Am J Clin Nutr. 2006 Oct \/ <strong>Selenium and coronary heart disease: a meta-analysis.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17023702\n<strong>12.<\/strong> J Trace Elem Med Biol. 2017 Dec \/ <strong>The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28965605\n<strong>13.<\/strong> <strong>Atherosclerosis<\/strong> \/ https:\/\/www.nhlbi.nih.gov\/health-topics\/atherosclerosis\n<strong>14.<\/strong> Front Aging Neurosci. 2014 \/ <strong>Nutritional status, oxidative stress and dementia: the role of selenium in Alzheimer's disease<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4147716\/\n<strong>15.<\/strong> Biometals. 2014 Jun \/ <strong>Homeostasis of metals in the progression of Alzheimer's disease.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24668390\n<strong>16.<\/strong> <strong>Lower brain and blood nutrient status in Alzheimer's disease: Results from meta-analyses<\/strong> \/ https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2352873717300409\n<strong>17.<\/strong> Am J Clin Nutr. 2011 Sep \/ <strong>French adults' cognitive performance after daily supplementation with antioxidant vitamins and minerals at nutritional doses: a post hoc analysis of the Supplementation in Vitamins and Mineral Antioxidants (SU.VI.MAX) trial.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21775560\n<strong>18.<\/strong> <strong>Effects of Brazil nut consumption on selenium status and cognitive performance in older adults with mild cognitive impairment: a randomized controlled pilot trial<\/strong> \/ https:\/\/link.springer.com\/article\/10.1007%2Fs00394-014-0829-2\n<strong>19. <\/strong>Arch Neurol. 2006 Dec \/ <strong>Mediterranean diet, Alzheimer disease, and vascular mediation.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17030648\n<strong>20.<\/strong> <strong>Adherence to a Mediterranean-Style Diet and Effects on Cognition in Adults: A Qualitative Evaluation and Systematic Review of Longitudinal and Prospective Trials<\/strong> \/ https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2016.00022\/full\n<strong>21.<\/strong> Int J Endocrinol. 2017 \/ <strong>Selenium and Thyroid Disease: From Pathophysiology to Treatment<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5307254\/\n<strong>22.<\/strong> <strong>How does the thyroid gland work?<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK279388\/\n<strong>23.<\/strong> <strong>Low Population Selenium Status Is Associated With Increased Prevalence of Thyroid Disease<\/strong> \/ https:\/\/academic.oup.com\/jcem\/article\/100\/11\/4037\/2836081\n<strong>24.<\/strong> <strong>Selenium Supplementation in the Treatment of Hashimoto's Thyroiditis: A Systematic Review and a Meta-analysis<\/strong> \/ https:\/\/www.liebertpub.com\/doi\/abs\/10.1089\/thy.2009.0351\n<strong>25.<\/strong> Mol Nutr Food Res \/ <strong>The influence of selenium on immune responses<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3723386\/\n<strong>26.<\/strong> Nutr Rev \/ <strong>The Role of Selenium in HIV Infection<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3066516\/\n<strong>27.<\/strong> Adv Nutr. 2015 Jan \/ <strong>Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4288282\/\n<strong>28.<\/strong> <strong>Asthma<\/strong> \/ https:\/\/www.nhlbi.nih.gov\/health-topics\/asthma\n<strong>29.<\/strong> Mol Aspects Med \/ <strong>Selenium and asthma<\/strong> \/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3246085\/\n<strong>30.<\/strong> Ann Clin Biochem. 2011 Jul \/ <strong>Role of certain trace minerals in oxidative stress, inflammation, CD4\/CD8 lymphocyte ratios and lung function in asthmatic patients.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21546427\/\n<strong>31.<\/strong> Bratisl Lek Listy. 2002 \/ <strong>Decreased consumption of corticosteroids after selenium supplementation in corticoid-dependent asthmatics.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12061082\n<strong>32.<\/strong> Cochrane Database Syst Rev. 2004 \/ <strong>Selenium supplementation for asthma.<\/strong>\/ https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15106206\n<strong>33.<\/strong> https:\/\/fdc.nal.usda.gov\/index.html\n<strong>34.<\/strong> <strong>Dietary Supplement Label Database<\/strong> \/ https:\/\/www.dsld.nlm.nih.gov\/dsld\/dailyvalue.jsp\n<strong>35.<\/strong> <strong>Natural variation of selenium in Brazil nuts and soils from the Amazon region<\/strong> \/ https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0045653517313711\n<strong>36.<\/strong> <strong>Selenium-Fact Sheet for Health Professionals<\/strong> \/ https:\/\/ods.od.nih.gov\/factsheets\/Selenium-HealthProfessional\/\n<strong>37.<\/strong> <strong>Selenium neurotoxicity in humans: Bridging laboratory and epidemiologic studies<\/strong> \/ https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378427413014227<\/pre><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Selenyumun Yararlar\u0131, Eksikli\u011fi, Fazlal\u0131\u011f\u0131 ve Daha Fazlas\u0131 G\u00fcn\u00fcm\u00fczde ad\u0131 ve etkileri yeni yeni bilinmeye ba\u015flayan Selenyum, sa\u011fl\u0131\u011f\u0131n\u0131z i\u00e7in \u00e7ok \u00f6nemlidir. Selenyum esansiyel bir mineraldir ve v\u00fccudunuz taraf\u0131ndan \u00fcretilemez. Bu y\u00fczden besinler yoluyla al\u0131nmas\u0131 gerekir. Sadece k\u00fc\u00e7\u00fck miktarlarda gereklidir ancak metabolizman\u0131z ve tiroid fonksiyonunuz da dahil olmak \u00fczere v\u00fccudunuzda ki bir\u00e7ok s\u00fcre\u00e7te \u00f6nemli bir rol oynar. &hellip; <a href=\"https:\/\/www.imucore24.com.tr\/sanal-magaza\/selenyum-ozellikleri\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Selenyum ve \u00d6zellikleri<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":8428,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[126],"tags":[],"_links":{"self":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts\/326"}],"collection":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/comments?post=326"}],"version-history":[{"count":1,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts\/326\/revisions"}],"predecessor-version":[{"id":8429,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/posts\/326\/revisions\/8429"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/media\/8428"}],"wp:attachment":[{"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/media?parent=326"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/categories?post=326"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.imucore24.com.tr\/sanal-magaza\/wp-json\/wp\/v2\/tags?post=326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}